Intraoperative blood salvage may shorten the lifespan of red blood cells within 3 days postoperatively: A pilot study

Autor: Shan-Shan Zuo, Qin Huang, Wen-Tong Meng, Xin-Yi Liao, Da-Ming Gou, Jie Zhang
Rok vydání: 2017
Předmět:
Adult
Male
Blood transfusion
Erythrocytes
Cell Survival
RBC-engulfing granulocyte
medicine.medical_treatment
Statistics as Topic
Blood Loss
Surgical

RBC lifespan
030204 cardiovascular system & hematology
Risk Assessment
03 medical and health sciences
Blood Transfusion
Autologous

Hemoglobins
0302 clinical medicine
Postoperative Complications
Risk Factors
Medicine
Humans
Orthopedic Procedures
Prospective Studies
Risk factor
Prospective cohort study
Blood Volume
business.industry
Intraoperative blood salvage
Operative Blood Salvage
Anemia
General Medicine
Odds ratio
Clinical Trial/Experimental Study
Middle Aged
Confidence interval
Clinical trial
Outcome and Process Assessment
Health Care

030220 oncology & carcinogenesis
Anesthesia
Erythrocyte Count
intraoperative blood salvage
Female
Hemoglobin
business
Research Article
Zdroj: Medicine
ISSN: 1536-5964
Popis: Background: Intraoperative blood salvage (IBS) recovers most lost blood, and is widely used in the clinic. It is unclear why IBS does not reduce long-term postoperative requirements for red blood cells (RBCs), and 1 possibility is that IBS affects RBC lifespan. Methods: Prospectively enrolled patients who underwent spine, pelvic, or femur surgery not involving allogeneic RBC transfusion were grouped based on whether they received IBS or not. Volumes of blood lost and of RBCs salvaged during surgery were recorded. Total blood cell counts, levels of plasma-free hemoglobin, and CD235a-positive granulocytes were determined perioperatively. Results: Although intraoperative blood loss was higher in the IBS group (n = 45) than in the non-IBS group (n = 52) (P
Databáze: OpenAIRE