Does the dose or type of gonadotropins affect the reproductive outcomes of poor responders undergoing modified natural cycle IVF (MNC-IVF)?

Autor: P, Drakopoulos, F, Di Guardo, L, Boudry, S, Mackens, M, De Vos, G, Verheyen, H, Tournaye, C, Blockeel
Přispěvatelé: Centre for Reproductive Medicine - Gynaecology, Clinical sciences, Reproductive immunology and implantation, Faculty of Medicine and Pharmacy, UZB Other, Biology of the Testis, Reproduction and Genetics
Rok vydání: 2022
Předmět:
Zdroj: European Journal of Obstetrics & Gynecology and Reproductive Biology. 278:95-99
ISSN: 0301-2115
DOI: 10.1016/j.ejogrb.2022.09.005
Popis: OBJECTIVE: Does the dose or type of gonadotropin affect the reproductive outcomes of poor responders undergoing IVF in a modified natural cycle (MNC-IVF)? STUDY DESIGN: This is a retrospective cohort study including patients attending a tertiary referral University Hospital from 1st January 2017 until 1st March 2020. All predicted poor responders (Poseidon groups 3 and 4) who underwent MNC-IVF in our center were included. Mild ovarian stimulation (rFSH/uFSH/hp-hMG) was started when a follicle with a mean diameter of 12-14 mm was observed on ultrasound scan; GnRH antagonist was added from the next day onwards. Mature oocytes were inseminated using ICSI. RESULTS: In total 484 patients undergoing 1398 cycles were included. Mean (SD) age and serum AMH were 38.2 (3.7) years and 0.28 (0.26) ng/ml, respectively. The daily dose of gonadotropins was either
Databáze: OpenAIRE