Free leucine supplementation during an 8-week resistance training program does not increase muscle mass and strength in untrained young adult subjects
| Autor: | Lúcio Flávio Soares-Caldeira, Mario Carlos Welin Balvedi, Francis Lopes Pacagnelli, Douglas Kratki da Silva, Alan Pablo Grala, Alex S. Ribeiro, Walquíria Batista de Andrade, Andreo Fernando Aguiar, Rubens Alexandre da Silva |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Time Factors Nutritional Supplementation Adolescent Clinical Biochemistry Placebo Biochemistry Muscle hypertrophy 03 medical and health sciences 0302 clinical medicine Double-Blind Method Leucine Internal medicine medicine Humans Young adult Leg press Muscle Skeletal 030109 nutrition & dietetics business.industry Organic Chemistry Resistance training Skeletal muscle 030229 sport sciences Surgery medicine.anatomical_structure Endocrinology Cross-Sectional Studies Physical Fitness Dietary Supplements Physical Endurance Female business |
| Zdroj: | Amino acids. 49(7) |
| ISSN: | 1438-2199 |
| Popis: | The purpose of this study was to examine the effects of free leucine supplementation on changes in skeletal muscle mass and strength during a resistance training (RT) program in previously untrained, young subjects. In a double-blind, randomized, placebo-controlled study, 20 healthy young (22 ± 2 years) participants were assigned to two groups: a placebo-supplement group (PLA, N = 10) or a leucine-supplement group (LEU, N = 10). Both groups underwent an 8-week hypertrophic RT program (2 days/week), consuming an equivalent amount of leucine (3.0 g/day in a single post-training dose) or placebo (cornstarch). Quadriceps muscle strength, cross-sectional area (CSA) of the vastus lateralis (VL), and rectus femoris (RF), as well as the habitual dietary intake were assessed before and after the 8-week intervention period. There was a similar improvement in muscle strength (Leg press, LEU: +33% vs. PLA: +37%; P > 0.05, and knee extension, LEU: +31% vs. PLA: 34%; P > 0.05) and CSA (VL, LEU: 8.9% vs. PLA: 9.6%; P > 0.05, and RF, LEU: +21.6% vs. PLA: + 16.4%; P > 0.05) in the both groups from pre- to post-training. In addition, there was no significant (P > 0.05) difference in daily dietary intake between the LEU and PLA groups before and after the intervention period. Free leucine supplementation (3.0 g/day post-training) does not increase muscle strength or CSA during RT in healthy young subjects consuming adequate dietary protein intake. |
| Databáze: | OpenAIRE |
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