Treatment of hemiballismus with stereotactic pallidotomy
Autor: | Kim J. Burchiel, Konstantin V. Slavin, Thomas K. Baumann |
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Rok vydání: | 2004 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Models Neurological Action Potentials Corpus Luysi Globus Pallidus Stereotaxic Techniques Thalamus Subthalamic Nucleus Monitoring Intraoperative Afferent medicine Humans Pallidotomy Aged Neurons Hemiballismus Afferent Pathways Brain Mapping Dyskinesias business.industry General Medicine Vascular lesion medicine.disease Subthalamic nucleus Globus pallidus nervous system Anesthesia Stereotaxic technique Catheter Ablation Female Surgery Neurology (clinical) Radiology business Microelectrodes |
Zdroj: | Neurosurgical Focus. 17:43-46 |
ISSN: | 1092-0684 |
Popis: | Hemiballismus is a relatively rare movement disorder that is characterized by uncontrolled, random, large-amplitude movements of the limbs. It is usually caused by a vascular lesion that involves the contralateral subthalamic nucleus (STN) (also known as the nucleus hypothalamicus or corpus luysi) and its afferent and efferent pathways. The authors present a case of medically intractable hemiballismus in a 70-year-old woman who was successfully treated with stereotactic posteroventral pallidotomy. In agreement with the data reported earlier by other groups, the microrecording performed during the pallidotomy showed a decreased rate of firing of the pallidal neurons, supporting the theory of impaired excitatory input from the STN to the internal part of the globus pallidus. Stereotactic pallidotomy may be the procedure of choice in the treatment of medically intractable hemiballismus. Intraoperative microrecording significantly improves the precision of the stereotactic targeting and should be considered a standard part of the pallidotomy protocol. |
Databáze: | OpenAIRE |
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