High Cardiovascular Risk in Older Men With Severe Peripheral Artery Calcification on High-Resolution Peripheral QCT Scans
| Autor: | Catherine Planckaert, Janina M. Patsch, Pawel Szulc, Roland Chapurlat, Dominique Foesser |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
Acute coronary syndrome medicine.medical_specialty Computed Tomography Angiography 030209 endocrinology & metabolism Disease 030204 cardiovascular system & hematology Risk Assessment Severity of Illness Index Peripheral Arterial Disease 03 medical and health sciences Sex Factors 0302 clinical medicine Forearm Predictive Value of Tests Internal medicine medicine Humans Prospective Studies Acute Coronary Syndrome Quantitative computed tomography Vascular Calcification Aged Aged 80 and over medicine.diagnostic_test business.industry Age Factors Middle Aged Prognosis medicine.disease Peripheral Arterial calcification medicine.anatomical_structure Lower Extremity Heart Disease Risk Factors Cardiology France Cardiology and Cardiovascular Medicine business Body mass index Calcification |
| Zdroj: | Arteriosclerosis, Thrombosis, and Vascular Biology. 41:1818-1829 |
| ISSN: | 1524-4636 1079-5642 |
| Popis: | Objective: Arterial calcification is associated with high cardiovascular risk. Our aim was to assess the utility of peripheral arterial calcification (PAC) in distal forearm and distal leg for the prediction of acute coronary syndrome (ACS) and major adverse cardiovascular event in older men. Approach and Results: In 815 home-dwelling older men, PAC was assessed on the scans of distal forearm and leg obtained by high-resolution peripheral quantitative computed tomography. PAC score (0–12) was calculated on the basis of the number and severity in small peripheral arteries. The information on ACS and major adverse cardiovascular event was collected prospectively for 8 years. PAC severity increased with age and body mass index ( P P P P P Conclusions: Severe PAC is associated with higher risk of ACS and major adverse cardiovascular event in older home-dwelling men, also in men without known ischemic heart disease. Incidentally found severe PAC can be a serious warning indicating high cardiovascular risk. |
| Databáze: | OpenAIRE |
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