Extraction of Plasminogen Activator from Canine Vascular Segments in Situ

Autor: S. Wasantapruek, K. N. von Kaulla
Rok vydání: 1969
Předmět:
Zdroj: Experimental Biology and Medicine. 132:830-834
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-132-34317
Popis: SummaryPlasminogen activator is easily recovered from canine veins in situ by solutions retained in vessel lumens, previously emptied of blood. The veins can be extracted repeatedly before they become exhausted. A pH of 5, low ion strength, and the presence of digitonon will enhance the plasminogen activator release. Low temperatures will block it. The external jugular vein generally yielded more plasminogen than did the femoral vein. The femoral artery yielded very little activator.
Databáze: OpenAIRE