| Autor: |
Li-Rong Wen, Ming Li, Wei-Si Guo, Mingzhe Zhu, Cheng-Cheng Zhou, Shu-Guang Xie |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Organicbiomolecular chemistry. 17(13) |
| ISSN: |
1477-0539 |
| Popis: |
A novel HTIB-promoted direct intramolecular dehydrogenative C–S bond coupling reaction of thioamides has been developed to provide 1,3-benzothiazine derivatives in good yields. The reaction proceeds smoothly to reach completion at room temperature within 1 min under metal-free conditions. This protocol provides a mild and efficient strategy for the synthesis of six-membered N,S-containing heterocycles. Preliminary mechanistic studies indicate that a spirocyclic intermediate might be involved. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
