Stevens - Johnson Syndrome and Toxic Epidermal Necrolysis; Extensive Review of Reports of Drug-Induced Etiologies, and Possible Therapeutic Modalities
| Autor: | Precious Etti, Princess Omenyi, Esther Olunu, Adegbenro Omotuyi John Fakoya, David Adeiza Otohinoyi, Favour Anthony, Precious Anthony |
|---|---|
| Přispěvatelé: | All Saints University School of Medicine, Dominica |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Drug
Toxic Epidermal Necrolysis medicine.medical_specialty media_common.quotation_subject Adverse drug reaction Stevens-Johnson Syndrome Drug hypersensitivity skin mucous membranes lcsh:Medicine Dermatology Review Article 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Medicine media_common Skin integumentary system business.industry Mucous membranes lcsh:R Stevens johnson General Medicine medicine.disease Therapeutic modalities Toxic epidermal necrolysis Etiology business 030217 neurology & neurosurgery |
| Zdroj: | Open Access Macedonian Journal of Medical Sciences, Vol 6, Iss 4, Pp 730-738 (2018) Open Access Macedonian Journal of Medical Sciences Open Access Macedonian Journal of Medical Sciences; Vol 6, No 4 (2018): Apr 15 (OAMJMS); 730-738 Open Access Macedonian Journal of Medical Sciences; Vol 6 No 4 (2018): Apr 15 (OAMJMS); 730-738 |
| ISSN: | 1857-9655 |
| Popis: | Stevens - Johnson Syndrome and Toxic Epidermal Necrolysis are adverse hypersensitivity reactions that affect the skin and mucous membranes. They are characterised by erythematous macules and hemorrhagic erosions of the mucous membranes. Epidermal detachments of varying degrees of severity also occur in these conditions. Various aetiologies are associated with these conditions, with adverse drug reaction being the most common. Though the worldwide incidence of these conditions is recorded as low, diverse types of medication are being observed to lead to these conditions. This review compiles information on the details of Stevens-Johnson syndrome and Toxic Epidermal Necrolysis, the pathophysiology, therapeutic management, and largely considers the drug-induced etiologies associated with these conditions. |
| Databáze: | OpenAIRE |
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