Neuromyelitis Optica Complicated by Ornithine Transcarbamylase Deficiency Treated Safely with Pulse Steroid Therapy

Autor:	Ichiro Imafuku, Jun Saito, Takashi Sunouchi, Takahiro Nakayama, Ryuto Yoshida, Mizuki Kitamura, Takuya Sasaki, Masayuki Ueda
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Adult medicine.medical_specialty medicine.medical_treatment Ornithine transcarbamylase Case Report 030204 cardiovascular system & hematology Steroid 03 medical and health sciences Eating 0302 clinical medicine Internal medicine Internal Medicine medicine Humans Hyperammonemia pulse steroid therapy Ornithine transcarbamylase deficiency Neuromyelitis optica Pulse (signal processing) business.industry Neuromyelitis Optica General Medicine urea cycle disorders medicine.disease Ornithine Carbamoyltransferase Deficiency Disease Steroid therapy Endocrinology ornithine transcarbamylase deficiency Urea cycle 030211 gastroenterology & hepatology Female business
Zdroj:	Internal Medicine
ISSN:	1349-7235 0918-2918
Popis:	Steroid administration to patients with urea cycle disorders can cause hyperammonemia. We encountered a 36-year-old woman with neuromyelitis optica (NMO) complicated by ornithine transcarbamylase (OTC) deficiency. By reducing the doses of steroids and adequate infusion management, we were able to administer pulse steroid therapy without any severe complications. This case indicates the safety of steroid treatment in patients with urea cycle disorders.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58254f9d8308df89221dcefa2fce2d2 http://europepmc.org/articles/PMC8580751 Zobrazit plný text záznamu