Effect of periodontal treatment on the glomerular filtration rate, reduction of inflammatory markers and mortality in patients with chronic kidney disease: A systematic review

Autor: François Gueyffier, Brigitte Grosgogeat, Emilie Kalbacher, Théo Delbove, Kerstin Gritsch, Patrice Nony, Delphine Maucort-Boulch, Laurent Juillard
Přispěvatelé: Laboratoire des Multimatériaux et Interfaces (LMI), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon, Hospices Civils de Lyon (HCL), Unité de Pharmacologie Clinique et d'Essais Thérapeutiques [Lyon] (UPCET - EZUS - UNIV Lyon), Hospices Civils de Lyon (HCL)-Faculté de Médecine Laennec, Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Edouard Herriot [CHU - HCL], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), CarMeN, laboratoire
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Teeth
Physiology
[SDV]Life Sciences [q-bio]
030232 urology & nephrology
Systemic inflammation
law.invention
0302 clinical medicine
Medical Conditions
Randomized controlled trial
Oral Diseases
law
Chronic Kidney Disease
Tooth loss
Medicine and Health Sciences
Prospective Studies
10. No inequality
Prospective cohort study
Multidisciplinary
3. Good health
[SDV] Life Sciences [q-bio]
Nephrology
Research Design
Medicine
medicine.symptom
Anatomy
Glomerular Filtration Rate
Research Article
medicine.medical_specialty
Drug Research and Development
Inflammatory Diseases
Science
Oral Medicine
Renal function
Research and Analysis Methods
03 medical and health sciences
Internal medicine
medicine
Renal Diseases
Humans
Clinical Trials
Renal Insufficiency
Chronic
Periodontitis
Periodontal Diseases
Pharmacology
Renal Physiology
business.industry
Biology and Life Sciences
Retrospective cohort study
030206 dentistry
medicine.disease
Randomized Controlled Trials
Jaw
Clinical Medicine
business
Digestive System
Head
Kidney disease
Zdroj: PLoS ONE, Vol 16, Iss 1, p e0245619 (2021)
PLoS ONE
PLoS ONE, Public Library of Science, 2021, 16 (1), pp.e0245619. ⟨10.1371/journal.pone.0245619⟩
PLoS ONE, 2021, 16 (1), pp.e0245619. ⟨10.1371/journal.pone.0245619⟩
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0245619⟩
Popis: Aim To assess the effect of periodontal treatment (PT) on glomerular filtration rate (GFR), systemic inflammation, or mortality in patients with chronic kidney disease (CKD). Methods A literature search was performed on PubMed and Web of Science databases on articles published until December 2019. The PRISMA guidelines were used throughout the manuscript. Results Of the total studies found, only 18 met the inclusion criteria; four retrospective and 14 prospective studies (including 3 randomized controlled trials–RCT). After PT, 3 studies investigated GFR, 2 found significant improvement; 11 (including 2 RCTs) investigated C-reactive protein levels, 9 found a significant improvement (including the 2 RCTs); 5 (including 3 RCTs) investigated Interleukine-6 level, 4 found a significant improvement (including 2 RCTs) and 2 studies evaluated mortality, one (retrospective study) found a significant difference. Conclusions Within the limitations of the present study, PT seems to improve CKD status, especially by reducing the systemic inflammation. Further RCTs are needed to confirm the results and specifically assess the influence of different types of PT in CKD patients. Taking into consideration the ability of PT to prevent further tooth loss and denutrition, early management of periodontitis is extremely important in patients with impaired renal function.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje