Comparison of ultrasound-guided thermal ablation and conventional thyroidectomy for benign thyroid nodules: a systematic review and meta-analysis
| Autor: | Shihui Guan, Hui Wang, Dengke Teng |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Thyroid nodules
Cancer Research medicine.medical_specialty Physiology Ablation Techniques medicine.medical_treatment Thermal ablation 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Physiology (medical) Medical technology medicine Humans ablation techniques R855-855.5 Ultrasonography Radiofrequency Ablation business.industry Thyroidectomy medicine.disease Ultrasound guided 030220 oncology & carcinogenesis Meta-analysis thyroid nodule thyroidectomy Radiology business |
| Zdroj: | International Journal of Hyperthermia, Vol 37, Iss 1, Pp 442-449 (2020) |
| ISSN: | 1464-5157 0265-6736 4201-9125 |
| DOI: | 10.1080/02656736.2020.1758802 |
| Popis: | Objective To compare the safety and efficacy of ultrasound-guided thermal ablation and conventional thyroidectomy for benign thyroid nodules (TNs) by performing a systematic review and meta-analysis. Methods We searched PubMed, Embase, Web of Science and Cochrane Library databases for clinical trials from the date of their inception to 1 April 2019. Two investigators independently examined the trials to select qualified studies, extracted relevant information and assessed the risk of bias according to the Cochrane Collaboration checklist (Oxford, UK). The primary study outcomes were safety (hoarseness, hypothyroidism and postoperative pain) and efficacy (symptom improvement, postoperative cosmetic effects and hospitalization time). This study is registered with PROSPERO (CRD42019125643). Results Seven studies involving 1289 patients were included. The results demonstrated that the incidences of hoarseness [odds ratio (OR) 0.33, 95% confidence interval (95% CI) (0.14, 0.79)], hypothyroidism [risk difference (RD) −0.31, 95% CI (−0.34, −0.28)] and postoperative pain [OR 0.35, 95% CI (0.25, 0.49)] were lower, and the hospitalization time was shorter [standard mean difference (SMD) −4.01, 95% CI (−4.22, −3.81)], in the thermal ablation group than in the conventional thyroidectomy group, and postoperative cosmetic effects were better [relative risk (RR) ratio 1.12, 95% CI (1.01, 1.24)] (p |
| Databáze: | OpenAIRE |
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