Carcinoma of the thyroid gland, with special reference to a clinicopathologic classification
| Autor: | George Crile, Robert S. Dinsmore, John B. Hazard |
|---|---|
| Rok vydání: | 1948 |
| Předmět: |
medicine.medical_specialty
Pathology Endocrinology Diabetes and Metabolism Clinical Biochemistry Biochemistry Endocrinology Internal medicine Neoplasms Parenchyma medicine Carcinoma Humans Thyroid Neoplasms Thyroid cancer business.industry Biochemistry (medical) Thyroid Cancer medicine.disease Lymphatic system medicine.anatomical_structure Papillary carcinoma Lymph business |
| Zdroj: | The Journal of clinical endocrinology and metabolism. 8(9) |
| ISSN: | 0021-972X |
| Popis: | CLINICAL ASPECTS FROM the clinical point of view carcinomas of the thyroid can be divided into two main groups, the papillary and the nonpapillary. Papillary carcinomas behave as lymphangioinvasive tumors and metastasize to lymph nodes, whereas nonpapillary carcinomas are hemangioinvasive and metastasize through the blood stream. The great differences in the clinical behavior and prognosis of these two groups of tumors can be explained by their respective tendencies to invade lymphatics and blood vessels. Papillary carcinomas tend to be nonencapsulated, or at least nonenucleable. If a capsule is present it is formed by sclerosis and is densely adherent to the surrounding thyroid tissue so that it cannot be “shelled out” like the differentiated nonpapillary carcinomas. It is perhaps because the papillary carcinomas originate in the parenchyma of the thyroid, which is well supplied with lymphatic vessels, that they tend to invade lymphatics. If the nonpapillary tumors arise in adenomas the absence or paucit... |
| Databáze: | OpenAIRE |
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