Microneedling in androgenetic alopecia; comparing two different depths of microneedles
| Autor: | Gita Faghihi, Farahnaz Fatemi Naeini, Fariba Iraji, Samin Nabavinejad, Fatemeh Mokhtari |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Dermatology Disease course Hair growth 030207 dermatology & venereal diseases 03 medical and health sciences Young Adult 0302 clinical medicine Medicine Humans In patient integumentary system business.industry Therapeutic effect Alopecia Middle Aged Depth of penetration Minoxidil 030220 oncology & carcinogenesis Lotion sense organs business medicine.drug Hair |
| Zdroj: | Journal of cosmetic dermatologyREFERENCES. 20(4) |
| ISSN: | 1473-2165 |
| Popis: | BACKGROUND Microneedling has shown to have positive therapeutic effects in treatment of androgenetic alopecia (AGA); however, the best microneedling protocol is still controversial. AIMS Investigating effect of microneedling with 2 different depths of penetration on promoting hair growth in patients with AGA. METHODS Sixty patients, in the age of 18-45 years old with moderate and severe AGA, were allocated into 3 groups of control: treatment with minoxidil 5% lotion; group A: treatment with minoxidil 5% lotion and biweekly microneedling with a depth of 1.2 mm and group B: treatment with minoxidil 5% lotion and biweekly microneedling with a depth of 0.6 mm during 12 weeks. Efficacy parameters including change of hair count and hair thickness from baseline and assessment of hair growth by patient and investigator were evaluated. RESULTS Compared with the baseline, a significant increase in hair count and hair thickness was observed in all three groups after completion of the treatment course (P < .05). The mean rise in hair count (P = .017) and hair thickness (P = .007) was significantly greater in group B compared with control group. Investigator's evaluation of hair regrowth was significantly greater in group A (P = .04) and group B (P = .007) compared with control group. CONCLUSION Microneedling with a depth of 0.6 mm in combination with minoxidil is more effective than minoxidil monotherapy in patients with AGA in terms of hair count and hair thickness. This depth of penetration tended to be more beneficial than depth of 1.2 mm. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|