Sympathetic ophthalmia: A comprehensive update

Autor:	Deepshikha Agrawal, Swapnil Parchand, Nikitha Ayyadurai, Aniruddha Agarwal, Anil Gangwe, Shashwat Behera, Priyavat Bhatia, Samyak Mulkutkar, Gulshan Barwar, Ramandeep Singh, Alok Sen, Manisha Agarwal
Rok vydání:	2022
Předmět:	Ophthalmology Adrenal Cortex Hormones Choroid Ophthalmia Sympathetic Humans
Zdroj:	Indian journal of ophthalmology. 70(6)
ISSN:	1998-3689
Popis:	Sympathetic ophthalmia is a rare, bilateral, granulomatous, panuveitis following penetrating trauma or surgery to one eye. Clinical presentation commonly occurs within the first year of trauma occurrence but can be delayed by several years. It manifests as acute/chronic granulomatous uveitis with yellowish-white choroidal lesions or Dalen-Fuchs nodules. Initially, patients respond rapidly to corticosteroid therapy, but a majority require long-term use of corticosteroid-sparing agents to prevent recurrences. The purpose of this review is to elaborate on the current understanding of the pathophysiology, the importance of multimodal imaging in early diagnosis, and the role of newer immunomodulatory and biological agents in recalcitrant cases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56a6c48a69380c5db7dd01469bf05ad https://pubmed.ncbi.nlm.nih.gov/35647958 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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