Consumption of yoghurt favours remission after faecal microbiota transplantation for chronic pouchitis
| Autor: | Ole Thorlacius-Ussing, Sabrina Just Kousgaard, Karina Frahm Kirk, Hans Linde Nielsen |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Pilot Projects Pouchitis Gut flora Gastroenterology Faecal microbiota transplantation Feces 03 medical and health sciences 0302 clinical medicine Internal medicine Humans Medicine Prospective Studies biology business.industry Enema Fecal Microbiota Transplantation Hepatology Yogurt biology.organism_classification medicine.disease Diet Yoghurt 030220 oncology & carcinogenesis Cohort Etiology 030211 gastroenterology & hepatology business Pouchoscopy |
| Zdroj: | Kousgaard, S J, Nielsen, H L, Kirk, K F & Thorlacius-Ussing, O 2020, ' Consumption of yoghurt favours remission after faecal microbiota transplantation for chronic pouchitis ', International Journal of Colorectal Disease, vol. 35, no. 10, pp. 1955-1958 . https://doi.org/10.1007/s00384-020-03648-1 |
| ISSN: | 1432-1262 0179-1958 |
| Popis: | PURPOSE: The gut microbiota is conceivably a key factor in the aetiology of pouchitis. Faecal microbiota transplantation (FMT) has been suggested as a promising new treatment for chronic pouchitis, where treatment options often are few. However, little is known about the influence of the diet on the clinical effects of FMT. We assessed the diet of patients with chronic pouchitis undergoing FMT to investigate the influence of diet on the clinical outcome after FMT.METHODS: Nine patients with chronic pouchitis were allocated to treatment with FMT delivered by enema from five faecal donors for 14 consecutive days in a 6-month prospective, open-label, single-centre cohort pilot study. A dietary questionnaire was completed at baseline for all patients and donors. Patients underwent a pouchoscopy at baseline and at 30-day follow-up, and the Pouchitis Disease Activity Index (PDAI) was assessed.RESULTS: Patients' diets were generally similar, when comparing patients in remission post-FMT (PDAI CONCLUSION: Gastroenterologist performing clinical studies on FMT for chronic pouchitis should be aware of dietary habits as contributing factors for the clinical effect of FMT. |
| Databáze: | OpenAIRE |
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