Synthesis of fused imidazole rings by sequential van Leusen/C–H bond activation

Autor:	Thomas G. Pagano, Vijaya Gracias, Stevan W. Djuric, Alan F. Gasiecki
Rok vydání:	2006
Předmět:	C h bond Chemistry Stereochemistry education Organic Chemistry General Medicine Biochemistry Medicinal chemistry humanities Catalysis chemistry.chemical_compound Reaction sequence Intramolecular force Drug Discovery Imidazole
Zdroj:	Tetrahedron Letters. 47:8873-8876
ISSN:	0040-4039
Popis:	A concise route to access fused imidazole rings employing the van Leusen three-component reaction followed by a Pd/Cu catalyzed intramolecular C-arylation is reported. The reaction was found to be general and the products were formed in moderate to excellent yields using the two-step reaction sequence.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5654e6f664aaa720ae0e29145238f37 https://doi.org/10.1016/j.tetlet.2006.10.051 Zobrazit plný text záznamu Full Text from ScienceDirect