Assessment of rates of structural change in glaucoma using imaging technologies
| Autor: | Robert N. Weinreb, Kaweh Mansouri, Christopher Kai-Shun Leung, Mauro T. Leite, Felipe A. Medeiros |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Diagnostic Imaging
medicine.medical_specialty genetic structures Scanning laser polarimetry Glaucoma Diagnostic Techniques Ophthalmological Ophthalmoscopy Optical coherence tomography Ophthalmology medicine Medical imaging Humans medicine.diagnostic_test business.industry medicine.disease Cambridge Ophthalmological Symposium eye diseases medicine.anatomical_structure Scanning Laser Polarimetry Disease Progression Imaging technology sense organs Tomography business Tomography Optical Coherence Optic disc |
| Zdroj: | Eye. 25:269-277 |
| ISSN: | 1476-5454 0950-222X |
| DOI: | 10.1038/eye.2010.202 |
| Popis: | To review the ability of current imaging technologies to provide estimates of rates of structural change in glaucoma patients. Review of literature. Imaging technologies, such as confocal scanning laser ophthalmoscopy (CSLO), scanning laser polarimetry (SLP), and optical coherence tomography (OCT), provide quantifiable and reproducible measurements of the optic disc and parapapillary retinal nerve fibre layer (RNFL). Rates of change as quantified by the rim area (RA) (for CSLO) and RNFL thickness (for SLP and OCT) are related to glaucoma progression as detected by conventional methods (eg, visual fields and optic disc photography). Evidence shows that rates of RNFL and RA loss are significantly faster in progressing compared with non-progressing glaucoma patients. Measurements of rates of optic disc and RNFL change are becoming increasingly precise and individualized. Currently available imaging technologies have the ability to detect and quantify progression in glaucoma, and their measurements may be suitable end points in glaucoma clinical trials. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|