Role of bacterial biofilms in chronic non-healing ulcers and effect of subinhibitory concentrations of Betadine and hydrogen peroxide on biofilms
| Autor: | Ethel Suman, M. Shashidhar Kotian, R. Madhavi |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Microbiology (medical)
Staphylococcal infections Microbiology chemistry.chemical_compound Anti-Infective Agents Staphylococcus epidermidis medicine Humans Hydrogen peroxide Povidone-Iodine Ulcer biology business.industry Biofilm General Medicine Bacterial Infections Hydrogen Peroxide biochemical phenomena metabolism and nutrition medicine.disease biology.organism_classification Cannula Catheter Infectious Diseases chemistry Biofilms Vancomycin business Bacteria medicine.drug |
| Zdroj: | The Journal of hospital infection. 73(1) |
| ISSN: | 1532-2939 |
| Popis: | a subinhibitory concentration of vancomycin (Z 1⁄4 3.408; P 1⁄4 0.001). There was also a significant correlation between the adherence of bacteria to catheter and cannula with biofilm production (P 1⁄4 0.002). Our study found that the subinhibitory concentration of vancomycin caused a significant decrease in adherence of bacteria to catheter and cannula material and these organisms also exhibited a significant decrease in biofilm formation. Vancomycin, the treatment of choice in many meticillin-resistant staphylococcal infections, has been proposed in combination for the treatment of Staphylococcus epidermidis infection. The results of our study show that the use of vancomycin has an added advantage of preventing the initial adherence of bacteria to prosthetic devices and thereby preventing biofilm formation. |
| Databáze: | OpenAIRE |
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