Platelet 3H-imipramine binding in bipolar patients
| Autor: | Giovanni Muscettola, Clemente Patrizio Giannini, Andrea Di Lauro |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Blood Platelets Male Imipramine medicine.medical_specialty Bipolar Disorder Receptors Drug 3h imipramine binding Protein content Internal medicine medicine Humans Platelet Biological Psychiatry Aged Blood collection Middle Aged Ligand (biochemistry) Control subjects Receptors Neurotransmitter Kinetics Psychiatry and Mental health Endocrinology Female Carrier Proteins Psychology Clinical psychology |
| Zdroj: | Psychiatry Research. 18:343-353 |
| ISSN: | 0165-1781 |
| DOI: | 10.1016/0165-1781(86)90019-3 |
| Popis: | Platelet 3H-imipramine binding was investigated in 31 control subjects and 19 hospitalized bipolar patients, either in the hypomanic or the depressed phase of illness. The mean Bmax value in the bipolar depressed patients did not differ significantly from that in the control subjects or the hypomanic patients. Differences in timing of the assay after blood collection, membrane preparation, protein content used in the assay, or binding of radioactive ligand to the equipment do not appear to explain the discrepancy between these results and previous findings. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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