Scintigraphy with nanocolloid Tc 99m in patients with small cell lung cancer, with special reference to bone marrow and hepatic metastasis
| Autor: | A Widding, S W Hansen, H H Hansen, I Stilbo, N Rossing |
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| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Pathology Lung Neoplasms Biopsy Whole body imaging chemistry.chemical_element Bone Neoplasms Technetium Scintigraphy Metastasis Bone Marrow medicine Carcinoma Humans Radiology Nuclear Medicine and imaging Colloids Prospective Studies Carcinoma Small Cell Radionuclide Imaging Prospective cohort study medicine.diagnostic_test business.industry Liver Neoplasms General Medicine Middle Aged medicine.disease medicine.anatomical_structure chemistry Female Radiology Bone marrow business |
| Zdroj: | European Journal of Nuclear Medicine. 16:717-719 |
| ISSN: | 1619-7089 0340-6997 |
| Popis: | Nineteen patients with newly diagnosed small cell lung cancer (SCLC) were examined with a nanocolloid Tc-99m bone marrow whole body imaging (scintigraphy) in order to detect bone marrow metastasis. Bilateral bone marrow biopsy taken from the posterior iliac crest was used as a reference. The scintigraphy was considered abnormal if a focal lesion was present and/or if the bone marrow activity expanded to more than one-third of the proximal part of the extremities. In 3 of the 19 patients, microscopical bone marrow metastasis and cold spots (focal lesions) on the scintigram were present. An additional 9 patients had expansion of the activity. Eight patients showed scintigraphic focal lesions in the liver. SCLC metastasis was confirmed in 4 patients, while 1 patient had focal necroses. The results indicate that cold spots rather than expansion of activity with bone marrow scintigraphy detected bone marrow involvement of the disease in patients with SCLC. |
| Databáze: | OpenAIRE |
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