Hyperthyroid Graves' Disease and Primary Hypothyroidism Caused by TSH Receptor Antibodies in Monozygotic Twins: Case Reports

Autor:	Yoshihiko Aizawa, Katsumi Yoshida, Noriyo Sayama, Keishi Abe, Hirunobu Hori, Naoki Nakasato, Hiroshi Fukazawa, Yoshinori Kiso, Jun-ichi Tani, Kouki Mori
Rok vydání:	1998
Předmět:	Adult endocrine system medicine.medical_specialty endocrine system diseases Endocrinology Diabetes and Metabolism Graves' disease Disease Pathogenesis Endocrinology Hypothyroidism Internal medicine Blocking antibody Diseases in Twins medicine Humans Autoantibodies biology business.industry Thyroid Primary hypothyroidism Autoantibody Receptors Thyrotropin Twins Monozygotic medicine.disease Graves Disease medicine.anatomical_structure biology.protein Female Antibody business hormones hormone substitutes and hormone antagonists Immunoglobulins Thyroid-Stimulating
Zdroj:	Endocrine Journal. 45:117-121
ISSN:	1348-4540 0918-8959
Popis:	A 33-year-old woman with signs and symptoms of hypothyroidism, including increased thyroid stimulating blocking antibody (TSBAb) activity, was referred for treatment by her local physician. Her monozygote twin was treated for hyperthyroid Graves' disease 10 years earlier. This case of hyperthyroidism and hypothyroidism in identical twins suggests the involvement of environmental factors in the pathogenesis of autoimmune thyroid diseases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54e76a5a100213f5d3a882dd0a08e30 https://doi.org/10.1507/endocrj.45.117 Zobrazit plný text záznamu