Hot-processed virgin coconut oil abrogates cisplatin-induced nephrotoxicity by restoring redox balance in rats compared to fermentation-processed virgin coconut oil

Autor:	Arunaksharan Narayanankutty, Varsha Rao, Sabah Shehabudheen, Achuthan C. Raghavamenon, Soorya Parathodi Illam
Rok vydání:	2020
Předmět:	Male food.ingredient Health Toxicology and Mutagenesis 010501 environmental sciences Toxicology 01 natural sciences Redox Antioxidants 03 medical and health sciences 0302 clinical medicine food Functional food Cisplatin induced nephrotoxicity Animals Food science Rats Wistar Fresh coconut 0105 earth and related environmental sciences Pharmacology Chemical Health and Safety Chemistry Coconut oil Public Health Environmental and Occupational Health Polyphenols General Medicine Rats Oxidative Stress Polyphenol Fermentation Coconut Oil Kidney Diseases Lipid Peroxidation Cisplatin Oxidation-Reduction 030217 neurology & neurosurgery
Zdroj:	Drug and chemical toxicology. 45(3)
ISSN:	1525-6014
Popis:	Virgin coconut oil (VCO) is a functional food oil prepared from fresh coconut kernel either by hot-processed (HPVCO) or fermentation-processed (FPVCO). The FPVCO has been widely explored for its pharmacological efficacy; while HPVCO, which has traditional uses, is less explored. The present study compared the phenolic content and nephroprotective effect of both these oils in male Wistar rats.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54d3f37cecdeb123d09ab204788dc9b https://pubmed.ncbi.nlm.nih.gov/33059468 Zobrazit plný text záznamu