Recurrent bullous lesions associated with familial Mediterranean fever: a case report
| Autor: | Ertan Yilmaz, H. I. Ozbudak, D. S. Cakcak, Mehmet Akif Ciftcioglu, E. Coban, Ayse Akman, Erkan Alpsoy |
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| Rok vydání: | 2009 |
| Předmět: |
Infertility
Adult Abdominal pain Pathology medicine.medical_specialty Erythema Familial Mediterranean fever Peritonitis Dermatology Gout Suppressants Lesion Blister Recurrence medicine Humans Direct fluorescent antibody integumentary system medicine.diagnostic_test business.industry medicine.disease Abdominal Pain Familial Mediterranean Fever Treatment Outcome Skin biopsy Female medicine.symptom business Colchicine |
| Zdroj: | Clinical and experimental dermatology. 34(2) |
| ISSN: | 1365-2230 |
| Popis: | Summary Familial Mediterranean fever (FMF) is an inherited, recurrent, inflammatory disease. Of its various cutaneous features, erysipelas-like erythema is the best known and most common skin lesion. We present a new case of FMF with recurrent bullous lesions. A 41-year-old woman was admitted to our clinic with tense bullae, 20 × 20 mm in diameter on the left shin. The patient had a history of fever, abdominal pain, peritonitis attacks and infertility. A lesional skin biopsy revealed subepidermal bullae and neutrophilic infiltration around dermal vessels. Direct immunofluorescence analysis was negative. Over the period of investigation, the lesion regressed spontaneously; 1 month later, a similar lesion appeared on the right wrist. Diagnosis of FMF was made according to the Tel-Hashomer criteria. Recognition of this peculiar skin lesion may lead to an earlier diagnosis of the disease. |
| Databáze: | OpenAIRE |
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