Development of dynorphin-like immunoreactive auditory nerve terminals in the chick
| Autor: | Amanda E McDaniel, Rebecca A Code |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Cochlear Nucleus
Nerve Endings endocrine system animal structures Chick Embryo Dynorphin Anatomy Vestibulocochlear Nerve respiratory system Biology Dynorphins Immunohistochemistry Cochlear nucleus Developmental Neuroscience Cell bodies embryonic structures Calcium concentration Animals Opioid peptide Chickens circulatory and respiratory physiology Developmental Biology |
| Zdroj: | Developmental Brain Research. 106:165-172 |
| ISSN: | 0165-3806 |
| Popis: | The novel discovery that auditory nerve terminals in the chick cochlear nucleus magnocellularis (NM) are immunoreactive for the opioid peptide dynorphin (DYN) was recently reported [3]. The present study examines the development of DYN-immunoreactivity (DYN-I) in auditory nerve terminals in NM from embryos through young post-hatch chicks. No DYN-I was observed in NM at embryonic day 13 (E13). DYN-I first appeared at E16 as short flat structures partially surrounding NM cell bodies. Around post-hatch day 1 (P1), these structures had a more rounded, chalice-type of morphology reminiscent of the specialized auditory nerve terminals found in birds, the end-bulbs of Held. At P6, most NM neurons were circumscribed by a prominent DYN-I calyceal-type of ending. By P13, fewer NM cells were ringed by this DYN-I and by the third post-hatch week, there was very little DYN-I in NM. There were no obvious differences in the density of DYN-I terminals across either the rostrocaudal length or the mediolateral width of NM at any age examined. These results suggest that during a restricted time of development, end-bulbs of Held in the chick NM contain DYN. |
| Databáze: | OpenAIRE |
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