Diagnostic utility of the HIV dementia scale and the international HIV dementia scale in screening for HIV-associated neurocognitive disorders among Spanish-speaking adults
| Autor: | David J. Hardy, Andrew J. Levine, Enrique Lopez, Cristina Yamakawa, Hussah T Al-Kharafi, Kimberly Smith, Alexander J Steiner, Nicholas S. Thaler, Karl Goodkin |
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| Rok vydání: | 2016 |
| Předmět: |
Male
050103 clinical psychology AIDS Dementia Complex neuropsychology Human immunodeficiency virus (HIV) HIV Infections Neuropsychological Tests Spanish Neurodegenerative medicine.disease_cause Latino/a 0302 clinical medicine Developmental and Educational Psychology Psychology education.field_of_study 05 social sciences Neuropsychology Hispanic or Latino Middle Aged Los Angeles AIDS Clinical Psychology Infectious Diseases Mental Health Neuropsychology and Physiological Psychology Scale (social sciences) cognitive disorders HIV/AIDS Female Cognitive Sciences Adult medicine.medical_specialty infectious disease Population Neurocognitive Disorders Article 03 medical and health sciences Acquired immunodeficiency syndrome (AIDS) Clinical Research Acquired Cognitive Impairment medicine Humans Dementia 0501 psychology and cognitive sciences Psychiatry education Receiver operating characteristic Prevention Neurosciences medicine.disease Brain Disorders Neurocognitive 030217 neurology & neurosurgery |
| Zdroj: | Applied neuropsychology. Adult, vol 24, iss 6 |
| ISSN: | 2327-9109 2327-9095 |
| Popis: | Given that neurocognitive impairment is a frequent complication of HIV-1 infection in Spanish-speaking adults, the limited number of studies assessing HIV-associated neurocognitive disorders (HAND) in this population raises serious clinical concern. In addition to being appropriately translated, instruments need to be modified, normed, and validated accordingly. The purpose of the current study was to examine the diagnostic utility of the HIV Dementia Scale (HDS) and International HIV Dementia Scale (IHDS) to screen for HAND in Spanish-speaking adults living with HIV infection. Participants were classified as either HAND (N = 47) or No-HAND (N = 53) after completing a comprehensive neuropsychological evaluation. Receiver operating characteristic analyses found the HDS (AUC = .706) was more sensitive to detecting HAND than the IHDS (AUC = .600). Optimal cutoff scores were 9.5 for the HDS (PPV = 65.2%, NPV = 71.4%) and 9.0 for the IHDS (PPV = 59.4%, NPV = 59.1%). Canonical Correlation Analysis found the HDS converged with attention and executive functioning. Findings suggest that while the IHDS may not be an appropriate screening instrument with this population, the HDS retains sufficient statistical validity and clinical utility to screen for HAND in Spanish-speaking adults as a time-efficient and cost-effective measure in clinical settings with limited resources. |
| Databáze: | OpenAIRE |
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