Evaluating antimicrobial activities of Acanthus ilicifolius L. and Heliotropium curassavicum L against bacterial pathogens: an in-vitro study
| Autor: | V. Veeramanikandan, Kamatchi Ramesh Kumar, Abdullah Al-Dosary Munirah, Rangasamy Suresh Babu, Ramasubramanian Arumugam, Chinnathambi Pothiraj, Atef Hatamleh Ashraf, Muthukrishnan Gobinath, P. Balaji, Ramkumar Shanthi |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
H. curassavicu
Phytochemicals Heliotropium Infectious and parasitic diseases RC109-216 Nutraceutical Anti-Infective Agents Acanthaceae Heliotropium curassavicum Escherichia coli Humans chemistry.chemical_classification biology Traditional medicine Plant Extracts Chemistry Public Health Environmental and Occupational Health Glycoside General Medicine Acanthus ilicifolius biology.organism_classification Antimicrobial Terpenoid Anti-Bacterial Agents Infectious Diseases Phytochemical A. ilicifolius Public aspects of medicine RA1-1270 Antibacterial activity |
| Zdroj: | Journal of Infection and Public Health, Vol 14, Iss 12, Pp 1927-1934 (2021) |
| ISSN: | 1876-0341 |
| Popis: | Background Biomedical research, recently, focus more on searching for biomasses that contain extractable biologically active components for formulating new drugs. Halophytes growing in hyper saline conditions are expected to produce stress alleviating bioactive compounds. These phytochemicals could be the better raw materials for formulating new drugs. Methods The purpose of this work was to describe physiologically active compounds from Acanthus ilicifolius and Heliotropium curassavicum that had antimicrobial, antioxidant and nutraceutical properties utilizing a variety of solvents. Analysis of bioactive compounds included the application of common phytochemical screening assays, proximate analysis, FTIR analysis and antioxidant assays. The disc diffusion technique was used to determine the antibacterial activity of the plant extracts. Results Highest extraction yield was observed with methanol. A. ilicifolius methanolic extracts included a variety of bioactive components, including alkaloids, saponins, phenolics, flavonoids, steroids, cardiac glycosides, tannins, and terpenoids. H. curassavicum extracts showed the presence of all the phytochemicals except cardiac glycosides. The overall phenolic concentration and antioxidant capacity of A. ilicifolius were substantially greater. The antimicrobial assays explored that among the tested bacterial pathogens viz., Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Streptococcus pneumoniae, significant level of control was observed in E. coli, K. pneumoniae and B. subtilis, which were significantly susceptible to both the plant extracts at a concentration of 50 μg/ml. Conclusion The reports from the current investigation explored the possibility of utilizing these halophytes in nutraceutical formulations. The current study sheds light on the possibility of halophytes as natural secondary metabolites and bioactive chemicals with potential for antimicrobials. |
| Databáze: | OpenAIRE |
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