Impact of Lens Care Solutions on Protein Deposition on Soft Contact Lenses
| Autor: | Omali, Negar Babaei, Heynen, Miriam, Subbaraman, Lakshman N., Papinski, Dominik, Lakkis, Carol, Smith, Sarah, Morgan, Philip, Berntsen, David A., Nichols, Jason J., Jones, Lyndon W., Mathew, Jessica H., Cox, Stephanie M., Bickle, Katherine M., Powell, Daniel R., Cox, Jared, Miller, William L., Wallace-Tucker, Ashley, Charrier, Sabrina, Chen, Yi Ju, Cardenas, Laura, Huerta, Sonia, Dionne, Karen, Maldonado-Codina, Carole, Plowright, Andrew, Howarth, Gillian, Chatterjee, Neil, Mirza, Aftab, Dumbleton, Kathy, Schulze, Marc, Moezzi, Amir M., Luensmann, Doerte, Ngo, William, Paquette, Lindsay, Srinivasan, Sruthi, Varikooty, Jalaiah, Johnson, Jane, Simpson, Marina, Voss, Brad Leona, Ryan, Lynn, Careless, Nadeera, Smith, Alexandra, Dantam, Jaya, McCanna, David, Hickson-Curran, Sheila B., Toubouti, Youssef, Fadli, Zohra, Lada, Mark Witold |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Materials science Adolescent Lysozyme Enzyme-Linked Immunosorbent Assay law.invention Young Adult 03 medical and health sciences 0302 clinical medicine Optics law Ophthalmology medicine Humans Protein deposition Aged Total protein business.industry Follow up studies Proteins Contact lens Middle Aged Daily wear Contact Lenses Hydrophilic Lens (optics) 030104 developmental biology Multicenter study 030221 ophthalmology & optometry Equipment Contamination Female Contact Lens Solutions Lens care solutions business Follow-Up Studies Optometry |
| Zdroj: | Omali, N B, Heynen, M, Subbaraman, L N, Papinski, D, Lakkis, C, Smith, S, Morgan, P, Berntsen, D A, Nichols, J J, Jones, L W, Mathew, J H, Cox, S M, Bickle, K M, Powell, D R, Cox, J, Miller, W L, Wallace-Tucker, A, Charrier, S, Chen, Y J, Cardenas, L, Huerta, S, Dionne, K, Maldonado-Codina, C, Plowright, A, Howarth, G, Chatterjee, N, Mirza, A, Dumbleton, K, Schulze, M, Moezzi, A M, Luensmann, D, Ngo, W, Paquette, L, Srinivasan, S, Varikooty, J, Johnson, J, Simpson, M, Voss, B L, Ryan, L, Careless, N, Smith, A, Dantam, J, McCanna, D, Hickson-Curran, S B, Toubouti, Y, Fadli, Z & Lada, M W 2016, ' Impact of lens care solutions on protein deposition on soft contact lenses ', Optometry and Vision Science, vol. 93, no. 8, pp. 963-972 . https://doi.org/10.1097/OPX.0000000000000928 |
| ISSN: | 1538-9235 1040-5488 |
| Popis: | Purpose. To evaluate the effect of four contemporary lens care solutions on total protein, total lysozyme, and active lysozyme extracted from three contact lens materials. Methods. Adapted contact lens wearers were recruited at three sites, and all subjects were randomly assigned to daily wear of either etafilcon A, galyfilcon A, or senofilcon A for 2 weeks. Four lens care solutions (Biotrue, OPTI-FREE PureMoist, RevitaLens OcuTec, and ClearCare) were used by each subject in random order with a new pair of lenses after a washout period between solutions of at least 4 days. After 2 weeks of daily wear, contact lenses were collected for analysis. Proteins were extracted from a subset of contact lenses (n = 568) and total protein, total lysozyme, and lysozyme activity were quantified using a modified Bradford assay, an enzyme-linked immunosorbent assay, and a micrococcal assay, respectively. Results. Higher levels of total protein were extracted from etafilcon A when used with Biotrue compared to other solutions (p = 0.0001). There were higher levels of total lysozyme extracted from galyfilcon A lenses when used with PureMoist than with Biotrue or Clear Care (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|