The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study
| Autor: | Hanan Jambi, Suhad Bahijri, Aliaa A. Alamoudi, Jawaher Al-Ahmadi, Ghada Ajabnoor, Anwar Borai, Jaakko Toumilehto, Rajaa Al Raddadi |
|---|---|
| Přispěvatelé: | Clinicum, Department of Public Health, University of Helsinki |
| Rok vydání: | 2021 |
| Předmět: |
Blood Glucose
Male Cross-sectional study Blood Pressure Cardiovascular Medicine 030204 cardiovascular system & hematology Vascular Medicine Biochemistry chemistry.chemical_compound Medical Conditions Endocrinology 0302 clinical medicine High-density lipoprotein Risk Factors Medicine and Health Sciences Medicine 030212 general & internal medicine 2. Zero hunger Multidisciplinary medicine.diagnostic_test Organic Compounds Monosaccharides gamma-Glutamyltransferase Lipids 3142 Public health care science environmental and occupational health 3. Good health Chemistry Cholesterol Cardiovascular Diseases Hypertension Physical Sciences Research Article Adult medicine.medical_specialty Endocrine Disorders Science Cardiology Carbohydrates 03 medical and health sciences Internal medicine Diabetes Mellitus Humans business.industry Organic Chemistry Chemical Compounds Biology and Life Sciences Cardiovascular Disease Risk medicine.disease Cross-Sectional Studies Glucose Blood pressure Dyslipidemia chemistry Metabolic Disorders Glycated hemoglobin business Lipid profile Body mass index |
| Zdroj: | PLoS ONE PLoS ONE, Vol 16, Iss 2, p e0246568 (2021) |
| ISSN: | 1932-6203 |
| Popis: | Population specific associations between cardiovascular disease with various risk factors including pre-hypertension and hypertension were reported. We aimed to investigate the association of higher than optimal blood pressure with measures of dysglycemia, dyslipidemia, and markers of inflammation in non-diabetic Saudi adults hoping to improve current Saudi guidelines to prevent cardiovascular disease. Volunteers were recruited randomly from public healthcare centers in Jeddah. Demographic information, blood pressure (BP), and anthropometric measurements were taken. Fasting blood samples were drawn, then again following 1-hour oral glucose tolerance test. Glycated hemoglobin, fasting plasma glucose (FPG), lipid profile, highly sensitive C- reactive protein, gamma glutamyl transferase, and 1-hour plasma glucose were measured. Complete data was found for 742 men and 592 women. Pre-hypertension was found in 47.2% of men, and 24.7% of women, while 15.1% of men, and 14.6% of women were hypertensive. Means of measured variables differed significantly between normotensive, pre-hypertensive, and hypertensive groups of men and women in gender specific manner. Association between measured variables and elevated BP, and hypertension were assessed using logistic regression models. After adjustment for age, body mass index and waist circumference, elevated blood pressure was associated with elevated triglycerides in men, while hypertension was significantly associated with elevated fasting plasma glucose, total cholesterol, triglycerides, low density lipoprotein- cholesterol, and low high density lipoprotein- cholesterol in men, and elevated triglycerides, and total cholesterol in women. Therefore, it is strongly recommended to measure lipid profile, specifically TG, for all diagnosed pre-hypertensive and hypertensive patients in addition to FPG for men. |
| Databáze: | OpenAIRE |
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