Ocular Motor System Control Models and the Cerebellum: Hypothetical Mechanisms
| Autor: | Louis F. Dell'Osso |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Cerebellum
medicine.medical_specialty Neurology genetic structures Eye Movements Ocular motor Models Neurological Nystagmus 050105 experimental psychology Smooth pursuit 03 medical and health sciences Saccadic intrusions 0302 clinical medicine Ocular Motility Disorders Cerebellar Diseases Medicine Animals Humans 0501 psychology and cognitive sciences business.industry 05 social sciences eye diseases Saccadic masking medicine.anatomical_structure Control system Neurology (clinical) medicine.symptom business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Cerebellum (London, England). 18(3) |
| ISSN: | 1473-4230 |
| Popis: | To review our studies and "top-down" models of saccadic intrusions and infantile nystagmus syndrome with the aim of hypothesizing areas of cerebellar connections controlling parts of the ocular motor subsystems involved in both types of function and dysfunction. The methods of eye-movement recording and modeling are described in detail in the cited references. Saccadic intrusions, such as square-wave jerks and square-wave oscillations, can be simulated by a single malfunction, whereas staircase saccadic intrusions required two independent malfunctions. The major infantile nystagmus syndrome waveforms are traceable to a failure to calibrate the damping ratio of the smooth pursuit system. The use of a behavioral ocular motor system model demonstrated how putative cerebellar dysfunctions could accurately simulate both the oscillations and the ocular motor responses seen in patients with both saccadic and pursuit disorders. |
| Databáze: | OpenAIRE |
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