Shortening of electrospun PLLA fibers by ultrasonication
| Autor: | Dorota Kołbuk, Beata Niemczyk-Soczynska, Judyta Dulnik, Oliwia Jeznach, Paweł Sajkiewicz |
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| Rok vydání: | 2021 |
| Předmět: |
010302 applied physics
chemistry.chemical_classification Materials science Sonication General Physics and Astronomy 02 engineering and technology Cell Biology Polymer 021001 nanoscience & nanotechnology 01 natural sciences Electrospinning law.invention Gel permeation chromatography chemistry Structural Biology law 0103 physical sciences General Materials Science Ultrasonic sensor Fiber Fragmentation (cell biology) Composite material 0210 nano-technology Filtration |
| Zdroj: | Micron (Oxford, England : 1993). 145 |
| ISSN: | 1878-4291 |
| Popis: | This research work is aimed at studying the effect of ultrasounds on the effectiveness of fiber fragmentation by taking into account the type of sonication medium, processing time, and various PLLA molecular weights. Fragmentation was followed by an appropriate filtration in order to decrease fibers length distribution. It was evidenced by fiber length determination using SEM that the fibers are shortened after ultrasonic treatment, and the effectiveness of shortening depends on the two out of three investigated parameters, mostly on the sonication medium, and processing time. The gel permeation chromatography (GPC) confirmed that such ultrasonic treatment does not change the polymers' molecular weight. Our results allowed to optimize the ultrasonic fragmentation procedure of electrospun fibers while preliminary viscosity measurements of fibers loaded into hydrogel confirmed their potential in further use as fillers for injectable hydrogels for regenerative medicine applications. |
| Databáze: | OpenAIRE |
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