Isolated renal mucormycosis presenting with bilateral renal artery thrombosis: a case report
| Autor: | Shalini Pilllai, P S Saneesh, Raghav Yelamanchi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Urology medicine.medical_treatment 030231 tropical medicine Case Reports Thrombophilia Organ transplantation Sepsis 03 medical and health sciences 0302 clinical medicine Case report medicine Mucormycosis Renal replacement therapy Septic thrombus Dialysis 0303 health sciences medicine.diagnostic_test 030306 microbiology business.industry Acute kidney injury Bilateral renal artery thrombosis medicine.disease Diseases of the genitourinary system. Urology Surgery RC870-923 Renal biopsy business |
| Zdroj: | African Journal of Urology African Journal of Urology, Vol 27, Iss 1, Pp 1-4 (2021) |
| ISSN: | 1961-9987 1110-5704 |
| Popis: | Background Mucormycosis is a rare infection caused by the fungus belonging to the order Mucorales. Mucormycosis predominantly affects immunocompromised individuals such as people with acquired immunodeficiency syndrome, blood malignancies, organ transplant, etc. Involvement of the kidneys usually occurs as a result of disseminated mucormycosis. We report a very rare case of isolated renal mucormycosis in an immunocompetant individual without any prior comorbidities who had an unusual presentation of mucormycosis. Case presentation A 17-year-old male student had presented to our emergency department with complaints of bilateral loin pain and fever for 10 days. There was no urine output for 2 days. Patient was in sepsis with acute kidney injury. A Doppler ultrasound of the abdomen revealed bilateral enlarged kidneys with absent blood flow in the renal vasculature. Dialysis was done, and patient was started on intravenous antibiotics. Patient was investigated for thrombophilia, the test results of which were normal. Sickle cell test was negative. Immunodeficiency screening was negative. Contrast-enhanced computed tomography revealed bilateral enlarged kidneys with bilateral renal artery thrombosis and mild ascitis. CT-guided renal biopsy was performed in the same sitting which revealed fungal hyphae in the background of necrotic glomeruli. Patient was started on liposomal amphotericin B with renal replacement therapy. However, patient deteriorated and succumbed to sepsis on the 4th day of admission. Conclusion Isolated renal mucormycosis with bilateral renal artery thrombosis is a very rare clinical scenario with high mortality. One must have a high degree of suspicion to diagnose renal mucormycosis at an early stage. |
| Databáze: | OpenAIRE |
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