The utility of dermoscopy in the diagnosis of evolving lesions of vitiligo
| Autor: | Sarvesh S Thatte, Uday Khopkar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
vitiligo
medicine.medical_specialty Pathology Ultraviolet Rays Cell Count Dermoscopy Dermatology Vitiligo Histopathological examination evolving lesions Depigmentation medicine Ultraviolet light lcsh:Dermatology Humans skin and connective tissue diseases Hypopigmentation medicine.diagnostic_test integumentary system business.industry Pigmentation lcsh:RL1-803 medicine.disease Hyperpigmentation polarized light and ultraviolet light Infectious Diseases Skin biopsy Melanocytes Histopathology medicine.symptom business |
| Zdroj: | Indian Journal of Dermatology, Venereology and Leprology, Vol 80, Iss 6, Pp 505-508 (2014) |
| ISSN: | 0378-6323 |
| Popis: | Background: Early lesions of vitiligo can be confused with various other causes of hypopigmentation and depigmentation. Few workers have utilized dermoscopy for the diagnosis of evolving lesions of vitiligo. Aim: To analyze the dermoscopic findings of evolving lesions in diagnosed cases of vitiligo and to correlate them histopathologically. Methods: Dermoscopy of evolving lesions in 30 diagnosed cases of vitiligo was performed using both polarized light and ultraviolet light. Result: On polarized light examination, the pigmentary network was found to be reduced in 12 (40%) of 30 patients, absent in 9 (30%), and reversed in 6 (20%) patients; 2 patients (6.7%) showed perifollicular hyperpigmentation and 1 (3.3%) had perilesional hyperpigmentation. A diffuse white glow was demonstrable in 27 (90%) of 30 patients on ultraviolet light examination. Melanocytes were either reduced in number or absent in 12 (40%) of 30 patients on histopathology. Conclusion: Pigmentary network changes, and perifollicular and perilesional hyperpigmentation on polarized light examination, and a diffuse white glow on ultraviolet light examination were noted in evolving vitiligo lesions. Histopathological examination was comparatively less reliable. Dermoscopy appears to be better than routine histopathology in the diagnosis of evolving lesions of vitiligo and can obviate the need for a skin biopsy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|