Salivary VIP concentrations are elevated in humans after acute stress
| Autor: | Roberta L. Moldow, Caitlin Colonna, Denise Alfano, Giovanni Ventre, Jennifer Smith |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty Saliva Adolescent Physiology Vasoactive intestinal peptide Neuropeptide Enzyme-Linked Immunosorbent Assay Biochemistry Glucagon Secretin Young Adult Cellular and Molecular Neuroscience chemistry.chemical_compound Endocrinology Stress Physiological Internal medicine medicine Humans Amylase Neurotransmitter chemistry.chemical_classification biology business.industry Amino acid chemistry biology.protein Female business Stress Psychological hormones hormone substitutes and hormone antagonists Vasoactive Intestinal Peptide |
| Zdroj: | Peptides. 49:27-31 |
| ISSN: | 0196-9781 |
| DOI: | 10.1016/j.peptides.2013.08.014 |
| Popis: | Salivary (s)-cortisol, s-amylase, s-DHEA are used extensively in stress research. Vasoactive Intestinal Peptide (VIP) is also detectable in saliva using a standard RIA kit. VIP is a 28 amino acid neuropeptide that belongs to the secretin/glucagon family of peptides and acts as a neurotransmitter/neuromodulator. VIP has also been detected in the parasympathetic nerves enervating the salivary glands. Here we measured the level of s-cortisol, s-DHEA, s-amylase and s-VIP in three different stress exercises of different duration and intensity. The results indicate that a brief intense exercise lasting minutes elicited a stress response with significant increases in s-cortisol, s-DHEA, s-amylase and s-VIP. A less rigorous exercise did not elicit a stress response with no significant increases in s-cortisol, s-DHEA, s-amylase and s-VIP. A longer intense exercise lasting hours elicited a stress response with significant increases only in s-cortisol. |
| Databáze: | OpenAIRE |
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