Controlling intercellular flow through mechanosensitive plasmodesmata nanopores
| Autor: | Karl Oparka, Kaare H. Jensen, Keunhwan Park, Jan Knoblauch |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Cell Membrane Permeability Osmotic shock Science General Physics and Astronomy Plant cell biology Cell Communication 02 engineering and technology Plasmodesma Endoplasmic Reticulum Mechanotransduction Cellular Article General Biochemistry Genetics and Molecular Biology Membrane biophysics Nanopores 03 medical and health sciences chemistry.chemical_compound Osmotic Pressure Plant development Mechanotransduction lcsh:Science Glucans Plant Physiological Phenomena Multidisciplinary Callose Plasmodesmata Biological Transport General Chemistry Applied mathematics 021001 nanoscience & nanotechnology Plant cell 030104 developmental biology chemistry Permeability (electromagnetism) Biophysics lcsh:Q Mechanosensitive channels 0210 nano-technology |
| Zdroj: | Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019) Nature Communications Park, K, Knoblauch, J, Oparka, K & Jensen, K H 2019, ' Controlling intercellular flow through mechanosensitive plasmodesmata nanopores ', Nature Communications, vol. 10, no. 1, 3564 . https://doi.org/10.1038/s41467-019-11201-0 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-019-11201-0 |
| Popis: | In plants, plasmodesmata (PD) are nanopores that serve as channels for molecular cell-to-cell transport. Precise control of PD permeability is essential to regulate processes such as growth and tissue patterning, photoassimilate distribution and defense against pathogens. Callose deposition modulates PD transport but little is known of the rapid events that lead to PD closure in response to tissue damage or osmotic shock. We propose a mechanism of PD closure as a result of mechanosensing. Pressure forces acting on the dumbbell-shaped ER-desmotubule complex cause it to be displaced from its equilibrium position, thus closing the PD aperture. The filamentous protein tethers that link the plasma membrane to the ER-desmotubule complex play a key role in determining the selectivity of the PD pore. This model of PD control compares favorably with experimental data on the pressure-generated closure of PD. Plasmodesmata channels connect neighbouring plant cells and respond to external stimuli via changes in permeability. Here Park et al. propose that mechanical forces can displace the dumbbell-shaped ER-desmotubule complex that spans the central plasmodesmatal cylinder leading to closure of the pore. |
| Databáze: | OpenAIRE |
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