The Potential Application of Allium Extracts in the Treatment of Gastrointestinal Cancers
| Autor: | Jacek Januszewski, Zuzanna Chilimoniuk, Robert Sitarz, Alicja Forma |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Allium extract
0301 basic medicine Colorectal cancer medicine.medical_treatment RC799-869 Pharmacology garlic 03 medical and health sciences 0302 clinical medicine Pancreatic cancer medicine esophageal cancer gastrointestinal cancers Chemotherapy Hepatology biology business.industry gastric cancer Gastroenterology food and beverages Diseases of the digestive system. Gastroenterology Esophageal cancer medicine.disease biology.organism_classification Antimicrobial 030104 developmental biology 030220 oncology & carcinogenesis Cancer cell Allium Liver cancer business |
| Zdroj: | Gastroenterology Insights, Vol 12, Iss 12, Pp 136-146 (2021) |
| ISSN: | 2036-7422 |
| DOI: | 10.3390/gastroent12020012 |
| Popis: | Herbal medicine is currently widely practiced, since natural resources are reported to alleviate side effects during oncological treatment while modifying cancer cell responses at the same time. Allium vegetables and their constituents have recently been extensively investigated due to the numerous possible beneficial properties, establishing them as an additional treatment modality in different cancers. According to the epidemiological evidence, as well as many in vivo and in vitro studies, the abovementioned substances seem to be effective in the prevention and inhibition of the progression of carcinogenesis. Due to high concentrations of organosulfur compounds, which exhibit anticarcinogenic, antimicrobial, as well as anti-inflammatory properties, Allium constituents are believed to constitute a promising prevention and supportive therapy for oncological patients. Besides, it was demonstrated that a combination of Allium extracts with chemotherapy provided satisfactory clinical outcomes while at the same time being cost-effective. The aim of this review was to present and discuss currently investigated Allium extracts and their effects on several gastrointestinal cancers including gastric, colon, liver, esophageal, and pancreatic cancer. |
| Databáze: | OpenAIRE |
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