Ph-activated nano-amorphous calcium phosphate-based cement to reduce dental enamel demineralization
| Autor: | Michael Powers, V.F. Passos, Hockin H.K. Xu, Michael D. Weir, Mary Anne S. Melo |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Calcium Phosphates
Materials science Biomedical Engineering Dental Cements Pharmaceutical Science Medicine (miscellaneous) chemistry.chemical_element Dentistry 02 engineering and technology Calcium 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine stomatognathic system Dental cement Humans Amorphous calcium phosphate Dental Enamel Cement Minerals Enamel paint business.industry Dental enamel 030206 dentistry General Medicine Hydrogen-Ion Concentration 021001 nanoscience & nanotechnology Phosphate Nanostructures Demineralization stomatognathic diseases chemistry visual_art visual_art.visual_art_medium 0210 nano-technology business Biotechnology |
| Zdroj: | Artificial Cells, Nanomedicine, and Biotechnology. 45:1778-1785 |
| ISSN: | 2169-141X 2169-1401 |
| Popis: | Enamel demineralization is destructive, esthetically compromised, and costly complications for orthodontic patients. Nano-sized amorphous calcium phosphate (NACP) has been explored to address this challenge. The 20% NACP-loaded ortho-cement notably exhibited favorable behavior on reducing demineralization of enamel around brackets in a caries model designed to simulate the carious attack. The 20% NACP-loaded ortho-cement markedly promotes higher calcium and phosphate release at a low pH, and the mineral loss was almost two fold lower and carious lesion depth decreased the by 1/3. This novel approach is promising co-adjuvant route for prevention of dental caries dissemination in millions of patients under orthodontic treatment. |
| Databáze: | OpenAIRE |
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