Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs

Autor:	Kaoru Iwabuchi, Chaker N. Adra, Rana A. Shuraim, Yasuhiko Uchida, Masanobu Chinami, Ryu Arita, Yoshiteru Muto
Rok vydání:	2019
Předmět:	Colorectal cancer medicine.medical_treatment lcsh:Medicine Case Report Case Reports miRNA analysis 030204 cardiovascular system & hematology Cell therapy 03 medical and health sciences 0302 clinical medicine Immune system microRNA medicine cancer lcsh:R5-920 business.industry PD‐1 lcsh:R Cancer adoptive cell therapy General Medicine Immunotherapy medicine.disease Cancer antigen 030220 oncology & carcinogenesis Cancer research immunotherapy lcsh:Medicine (General) Mirna microarray business
Zdroj:	Clinical Case Reports, Vol 7, Iss 11, Pp 2156-2164 (2019) Clinical Case Reports
ISSN:	2050-0904
DOI:	10.1002/ccr3.2343
Popis:	A 60‐year‐old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC‐ACT) causing induction of anti‐oncogenic and anti‐PD‐L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC‐ACT, metastases have been arrested, and the patient reports good quality of life.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4fd9b9bfb5403f7c17d7c5082a737ea https://doi.org/10.1002/ccr3.2343 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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