Thickness Influence on In Vitro Biocompatibility of Titanium Nitride Thin Films Synthesized by Pulsed Laser Deposition
| Autor: | Liviu Duta, Marcela Socol, Andrei C. Popescu, M.-A. Husanu, Florin Miculescu, George E. Stan, Sorin Moga, Iuliana Urzica, Irina Zgura, Ion N. Mihailescu, Adrian C. Popa |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
cytocompatibility
Materials science Biocompatibility Scanning electron microscope Analytical chemistry chemistry.chemical_element 02 engineering and technology 010402 general chemistry 01 natural sciences lcsh:Technology Pulsed laser deposition chemistry.chemical_compound X-ray photoelectron spectroscopy titanium nitride medical instrument pull-out adherence pulsed laser deposition General Materials Science Thin film lcsh:Microscopy lcsh:QC120-168.85 lcsh:QH201-278.5 lcsh:T 021001 nanoscience & nanotechnology equipment and supplies Titanium nitride 0104 chemical sciences Chemical engineering chemistry lcsh:TA1-2040 lcsh:Descriptive and experimental mechanics lcsh:Electrical engineering. Electronics. Nuclear engineering 0210 nano-technology Tin lcsh:Engineering (General). Civil engineering (General) lcsh:TK1-9971 Titanium |
| Zdroj: | Materials, Vol 9, Iss 1, p 38 (2016) Materials; Volume 9; Issue 1; Pages: 38 |
| ISSN: | 1996-1944 |
| Popis: | We report a study on the biocompatibility vs. thickness in the case of titanium nitride (TiN) films synthesized on 410 medical grade stainless steel substrates by pulsed laser deposition. The films were grown in a nitrogen atmosphere, and their in vitro cytotoxicity was assessed according to ISO 10993-5 [1]. Extensive physical-chemical analyses have been carried out on the deposited structures with various thicknesses in order to explain the differences in biological behavior: profilometry, scanning electron microscopy, atomic force microscopy, X-ray photoelectron spectroscopy (XPS), X-ray diffraction and surface energy measurements. XPS revealed the presence of titanium oxynitride beside TiN in amounts that vary with the film thickness. The cytocompatibility of films seems to be influenced by their TiN surface content. The thinner films seem to be more suitable for medical applications, due to the combined high values of bonding strength and superior cytocompatibility. |
| Databáze: | OpenAIRE |
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