Engineering Yarrowia lipolytica to produce advanced biofuels: current status and perspectives
| Autor: | Xiao-Jun Ji, Kaifeng Wang, Lu Ran, Rodrigo Ledesma-Amaro, Lizhen Cao |
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| Přispěvatelé: | Biotechnology and Biological Sciences Research Council (BBSRC), The Royal Society, British Council (UK) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Yarrowia lipolytica
Engineering Technology Environmental Engineering LIMONENE Energy & Fuels THIOESTERASES FUELS FEEDSTOCKS Yarrowia Bioengineering LIPOXYGENASE Metabolic engineering Synthetic biology BIOSYNTHESIS Fatty acids Waste Management and Disposal Science & Technology biology Advanced Biofuels HETEROLOGOUS PRODUCTION Renewable Energy Sustainability and the Environment business.industry Terpenes Agriculture General Medicine Energy security biology.organism_classification Renewable energy CONVERSION Biotechnology & Applied Microbiology Metabolic Engineering Biofuel Biofuels Synthetic Biology Biochemical engineering FATTY-ACIDS Sustainable production business Agricultural Engineering LIPID-ACCUMULATION Life Sciences & Biomedicine Biotechnology |
| Popis: | Energy security and global climate change have necessitated the development of renewable energy with net-zero emissions. As alternatives to traditional fuels used in heavy-duty vehicles, advanced biofuels derived from fatty acids and terpenes have similar properties to current petroleum-based fuels, which makes them compatible with existing storage and transportation infrastructures. The fast development of metabolic engineering and synthetic biology has shown that microorganisms can be engineered to convert renewable feedstocks into these advanced biofuels. The oleaginous yeast Yarrowia lipolytica is rapidly emerging as a valuable chassis for the sustainable production of advanced biofuels derived from fatty acids and terpenes. Here, we provide a summary of the strategies developed in recent years for engineering Y. lipolytica to synthesize advanced biofuels. Finally, efficient biotechnological strategies for the production of these advanced biofuels and perspectives for future research are also discussed. |
| Databáze: | OpenAIRE |
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