Pattern of platelet-associated immunoglobulin (classes and IgG subclasses) in childhood immune thrombocytopenic purpura
| Autor: | Sten Petersen, Ellen Taaning |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Blood Platelets
Male Enzyme-Linked Immunosorbent Assay Immunoglobulin E Immunoglobulin G Subclass Autoimmune Diseases hemic and lymphatic diseases Immunopathology Humans Medicine Platelet Child Autoantibodies biology business.industry Autoantibody Infant Hematology General Medicine medicine.disease Thrombocytopenic purpura Purpura Thrombocytopenic Child Preschool Immunology biology.protein Female Antibody business |
| Zdroj: | European Journal of Haematology. 41:449-453 |
| ISSN: | 1600-0609 0902-4441 |
| DOI: | 10.1111/j.1600-0609.1988.tb00226.x |
| Popis: | Platelet-associated Ig classes and IgG subclasses were studied by a semiquantitative platelet ELISA test in 17 children with immune thrombocytopenic purpura (ITP). An elevation of PAIg was found in 94% of the children. In nearly all cases increased amounts of PAIgG of subclass G1 was seen, and in half of the cases increased amounts of PAIgM were also seen. No statistical difference in the composition of PAIg classes and PAIgG subclasses in acute and in chronic ITP was found. However, a correlation of increased amount of PAIgG3 and very low platelet count (20 x 10(9)/l) was observed. |
| Databáze: | OpenAIRE |
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