Endoluminal formalin application for haemorrhagic radiation proctitis
Autor: | Frederick L Vyas, V. Mathai, B. Selvamani, S. R. Banerjee Jesudason, S. John |
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Rok vydání: | 2006 |
Předmět: |
Adult
medicine.medical_specialty Radiation proctitis medicine.medical_treatment Colonoscopy Chronic radiation proctitis Hemostatics Formaldehyde Partial response Humans Medicine Proctitis Prospective Studies Radiation Injuries Prospective cohort study Complete response Aged Radiotherapy medicine.diagnostic_test business.industry Gastroenterology Middle Aged medicine.disease Surgery Radiation therapy Treatment Outcome Female Gastrointestinal Hemorrhage Complication business Follow-Up Studies |
Zdroj: | Colorectal Disease. 8:342-346 |
ISSN: | 1463-1318 1462-8910 |
Popis: | Background Radiation proctitis is a common complication following radiation therapy for pelvic malignancies. This is associated with significant morbidity which adversely affects the quality of life. Local application of formalin has been used effectively in the treatment of radiation proctitis. Methodology Thirty patients with haemorrhagic radiation proctitis who underwent endoluminal application of 4% formalin between January 1998 to October 2002 were followed up prospectively to assess the efficacy of the treatment. Results The follow up ranged from 5 to 36 months (mean 18.1 months). Nineteen (63.3%) patients had complete response to formalin application while 7 (23.3%) patients had partial response. There were 4 (13.3%) failures. No procedure related complication was observed. Conclusion Local application of formalin is a simple, safe, inexpensive and fairly effective outpatient treatment modality for chronic radiation proctitis. |
Databáze: | OpenAIRE |
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