Endoluminal formalin application for haemorrhagic radiation proctitis

Autor: Frederick L Vyas, V. Mathai, B. Selvamani, S. R. Banerjee Jesudason, S. John
Rok vydání: 2006
Předmět:
Zdroj: Colorectal Disease. 8:342-346
ISSN: 1463-1318
1462-8910
Popis: Background Radiation proctitis is a common complication following radiation therapy for pelvic malignancies. This is associated with significant morbidity which adversely affects the quality of life. Local application of formalin has been used effectively in the treatment of radiation proctitis. Methodology Thirty patients with haemorrhagic radiation proctitis who underwent endoluminal application of 4% formalin between January 1998 to October 2002 were followed up prospectively to assess the efficacy of the treatment. Results The follow up ranged from 5 to 36 months (mean 18.1 months). Nineteen (63.3%) patients had complete response to formalin application while 7 (23.3%) patients had partial response. There were 4 (13.3%) failures. No procedure related complication was observed. Conclusion Local application of formalin is a simple, safe, inexpensive and fairly effective outpatient treatment modality for chronic radiation proctitis.
Databáze: OpenAIRE