Antimicrobial monomeric and dimeric diterpenes from the leaves of Helichrysum tenax var tenax
| Autor: | K. Esther Mudau, Siegfried E. Drewes, Sandy van Vuuren, Alvaro M. Viljoen |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Tenax
Bacillus cereus Microbial Sensitivity Tests Plant Science Horticulture Malonic acid Biochemistry chemistry.chemical_compound Anti-Infective Agents Staphylococcus epidermidis Organic chemistry Molecular Biology Helichrysum Plants Medicinal biology Plant Extracts Fungi Esters General Medicine Asteraceae biology.organism_classification Antimicrobial Malonates Plant Leaves chemistry Diterpenes Diterpene Dimerization |
| Zdroj: | Phytochemistry. 67:716-722 |
| ISSN: | 0031-9422 |
| DOI: | 10.1016/j.phytochem.2005.12.015 |
| Popis: | The hexane extract of fresh air-dried leaves of Helichrysum tenax (Asteraceae) afforded ent-beyer-15-en-19-ol (1), its 4-epimer ent-beyer-15-en-18-ol (2), 15beta,16beta-epoxide-ent-beyeran-19-ol (3), as well as (4) consisting of two units of (1) linked as a diester of malonic acid, and (5), a compound. Its constituents are (1) and (3) also linked as a diester of malonic acid. The leaves of the plant are densely covered in fine glandular trichomes. These are extremely sticky and exude a mixture of the above diterpenes. Antimicrobial tests showed that (1), in particular, was highly active (3.1 and 3.6 microg/ml) against Bacillus cereus and Staphylococcus epidermidis, respectively. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect