Serum Liver Fibrosis Markers in the Prognosis of Liver Cirrhosis: A Prospective Observational Study
| Autor: | Ying Peng, Xia Zhang, Jiang Chen, Xueying Wang, Xu Liu, Feifei Hou, Hao Lin, Yongguo Zhang, Hezhi Wang, Li-Nan Ren, Zhong-min Cui, Yanlin Zhang, Han Deng, Hongyu Li, Yue Hou, Jia-jun Zhao, Xiaodong Shao, Chunyan Wu, Chunlian Xia, Xueyan Li, Xiaozhong Guo, Xingshun Qi, Di Wang, Jinling Wang |
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| Rok vydání: | 2016 |
| Předmět: |
Liver Cirrhosis
Adult Collagen Type IV Male medicine.medical_specialty Pathology Cirrhosis Survival Gastroenterology 03 medical and health sciences Hepatitis B Chronic 0302 clinical medicine Clinical Research Fibrosis Internal medicine medicine Humans Prospective Studies Hyaluronic Acid Prospective cohort study Aged Aged 80 and over Receiver operating characteristic business.industry Area under the curve General Medicine Odds ratio Middle Aged Hepatitis B Prognosis medicine.disease Peptide Fragments Confidence interval ROC Curve 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Laminin business Biomarkers Procollagen |
| Zdroj: | Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 |
| DOI: | 10.12659/msm.900441 |
| Popis: | BACKGROUND The prognostic role of serum liver fibrosis markers in cirrhotic patients remains unclear. We performed a prospective observational study to evaluate the effect of amino-terminal pro-peptide of type III pro-collagen (PIIINP), collagen IV (CIV), laminin (LN), and hyaluronic acid (HA) on the prognosis of liver cirrhosis. MATERIAL AND METHODS All patients who were diagnosed with liver cirrhosis and admitted to our department were prospectively enrolled. PIIINP, CIV, LN, and HA levels were tested. RESULTS Overall, 108 cirrhotic patients were included. Correlation analysis demonstrated that CIV (coefficient r: 0.658, p |
| Databáze: | OpenAIRE |
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