Dietary nutrient levels alter the metabolism of arginine family amino acids in the conceptus of Huanjiang mini-pigs
Autor: | Yehui Duan, Yue Zhao, Qian Zhu, Qiaoli Cai, Huawei Li, Xiangfeng Kong, Zhanbin Wang, Yulong Yin |
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Rok vydání: | 2018 |
Předmět: |
Male
Arginine 030309 nutrition & dietetics Swine 03 medical and health sciences 0404 agricultural biotechnology Nutrient Pregnancy Placenta medicine Conceptus Animals Amino Acids reproductive and urinary physiology chemistry.chemical_classification 0303 health sciences Fetus Nutrition and Dietetics Chemistry Skeletal muscle 04 agricultural and veterinary sciences Metabolism Nutrients Embryo Mammalian 040401 food science Amino acid medicine.anatomical_structure Biochemistry embryonic structures Swine Miniature Female Agronomy and Crop Science Food Science Biotechnology |
Zdroj: | Journal of the science of food and agriculture. 99(5) |
ISSN: | 1097-0010 |
Popis: | The arginine family amino acids (AFAAs) exert important roles in the metabolism, growth and development of the conceptus. However, to date, few studies have investigated the effects of maternal nutrient levels on the concentrations and metabolism of AFAAs in the conceptus.Compared to low nutrient diets, high nutrient diets increased (P 0.05) the concentrations of citrulline and proline (Pro) in plasma; the concentrations of arginine, glutamine, Pro and ornithine (Orn) in the amniotic fluid; and the concentrations of all detected AFAAs in the allantoic fluid, which were most pronounced on day 45 of pregnancy. High nutrient diets upregulated (P 0.05) mRNA expression of arginase I (Arg I), Pro oxidase and spermidine synthetase (SRM) in the fetal placenta, as well as Arg II, SRM and spermine synthetase (SMS) expression in the fetal liver (most pronounced on day 45 of pregnancy). The same effect was observed for mRNA expression of NO synthase and Orn aminotransferase (OAT), mainly on day 110 of pregnancy, and for mRNA expression of Arg I, Arg II, OAT, Orn decarboxylase and SMS throughout pregnancy. High nutrient diets upregulated (P 0.05) mRNA expression of YHigh nutrient diets increased the concentration and transport of AFAAs in the mothers and conceptus, which likely improves growth and development of the conceptus. © 2018 Society of Chemical Industry. |
Databáze: | OpenAIRE |
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