Antioxidant, antimicrobial and cytotoxicity potential of n-hexane extract of Cayratia trifolia L
| Autor: | Chella Perumal Palanisamy, Mani Panagal, Bhuvaneswari Meganathan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cayratia trifolia
Antioxidant biology Traditional medicine Chemistry Cell growth medicine.medical_treatment General Medicine Antimicrobial activity biology.organism_classification Antimicrobial n-hexane extract Antioxidant activity Cell culture medicine MTT assay Agar diffusion test Cytotoxicity activity Cytotoxicity Research Article |
| Zdroj: | Bioinformation |
| ISSN: | 0973-2063 0973-8894 |
| Popis: | It is of interest to analyze the antioxidant, antimicrobial and cytotoxicity activity of n-hexane extract of Cayratia trifolia L. (C. trifolia). The antimicrobial activity of n-hexane extract of C. trifolia was determined using disc diffusion method against six selected pathogenic microorganisms. The cytotoxicity potential of n-hexane plant extract was also studied against A2780 cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Results, n-hexane extract of C. trifolia possess significant antioxidant activity with significant IC50 values in radical scavenging assays. In antimicrobial studies, the maximum zone of inhibition was found in the range of 19.0 ą 0.1 to 22.0 ą 0.1 mm. In MTT assay, inhibition of cell growth with minimal IC50 values of 46.25ą0.42μg/mL against A2780 cell lines was observed. Thus, n-hexane extract of C. trifolia is a possible antioxidant, antimicrobial and cytotoxicity agent. |
| Databáze: | OpenAIRE |
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