Hepatitis B or hepatitis C coinfection in HIV-infected pregnant women in Europe
| Autor: | Megan Landes, Igor Semenenko, Patricia Barlow, Valeria Savasi, Svetlana Posokhova, Claire Thorne, Pasquale Martinelli, Andrej Stelmah, Marie-Louise Newell, Ruslan Malyuta, Cecilia Tibaldi, Simona Fiore |
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| Přispěvatelé: | Landes, M, Newell, Ml, Barlow, P, Fiore, S, Malyuta, R, Martinelli, Pasquale, Posokhova, S, Savasi, V, Semenenko, I, Stelmah, A, Tibaldi, C, Thorne, C. |
| Rok vydání: | 2008 |
| Předmět: |
Adult
medicine.medical_specialty HBsAg Adolescent HIV Infections Cohort Studies Young Adult Hepatitis B Chronic Pregnancy Risk Factors Internal medicine Antiretroviral Therapy Highly Active Epidemiology medicine Prevalence Humans Pharmacology (medical) Young adult Hepatitis B Surface Antigens business.industry Health Policy virus diseases Odds ratio Hepatitis C Hepatitis B Hepatitis C Antibodies Hepatitis C Chronic medicine.disease digestive system diseases CD4 Lymphocyte Count Europe Infectious Diseases Logistic Models Immunology Coinfection RNA Viral Female Serostatus business |
| Zdroj: | HIV medicine. 9(7) |
| ISSN: | 1468-1293 |
| Popis: | Objectives The aim of the study was to investigate the prevalence of and risk factors for hepatitis C or B virus (HCV or HBV) coinfection among HIV-infected pregnant women, and to investigate their immunological and virological characteristics and antiretroviral therapy use. Methods Information on HBV surface antigen (HBsAg) positivity and HCV antibody (anti-HCV) was collected retrospectively from the antenatal records of HIV-infected women enrolled in the European Collaborative Study and linked to prospectively collected data. Results Of 1050 women, 4.9% [95% confidence interval (CI) 3.6–6.3] were HBsAg positive and 12.3% (95% CI 10.4–14.4) had anti-HCV antibody. Women with an injecting drug use(r) (IDU) history had the highest HCV-seropositivity prevalence (28%; 95% CI 22.8–35.7). Risk factors for HCV seropositivity included IDU history [adjusted odds ratio (AOR) 2.92; 95% CI 1.86–4.58], age (for ≥35 years vs. |
| Databáze: | OpenAIRE |
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