Cytopathogenic effect in cardiac myocytes but not in cardiac fibroblasts is correlated with reovirus-induced acute myocarditis
| Autor: | Barbara Sherry, C J Baty |
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| Předmět: |
Myocarditis
viruses Immunology Mice Inbred Strains Biology Reoviridae Virus Replication Microbiology Virus Mice Virology medicine Myocyte Animals Fibroblast Cells Cultured Cytopathic effect Myocardium Cardiac myocyte Heart Fibroblasts medicine.disease Reoviridae Infections medicine.anatomical_structure Viral replication Animals Newborn Cell culture Insect Science cardiovascular system Research Article |
| Zdroj: | Scopus-Elsevier |
| Popis: | A panel of reovirus strains was used to compare myocarditic potential with induction of cytopathic effect in primary cardiac myocyte and cardiac fibroblast cultures. The results suggest that viral cytopathogenicity in cardiac myocytes, but not in cardiac fibroblasts, is a determinant of reoviral myocarditis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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