Extended spectrum β-lactamase producingEscherichia coliandKlebsiella pneumoniae: critical tools for antibiotic resistance pattern
| Autor: | Nagarajan Padmini, Natesan Sivakumar, Gopal Selvakumar, Antony Alex Kennedy Ajilda |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.drug_class Klebsiella pneumoniae 030106 microbiology Antibiotics Microbial Sensitivity Tests Drug resistance medicine.disease_cause Applied Microbiology and Biotechnology beta-Lactamases Microbiology Third generation cephalosporins 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Immune system Drug Resistance Multiple Bacterial Escherichia coli medicine Humans 030212 general & internal medicine Escherichia coli Infections Cross Infection biology General Medicine biochemical phenomena metabolism and nutrition biology.organism_classification Enterobacteriaceae Virology Anti-Bacterial Agents Cephalosporins Klebsiella Infections |
| Zdroj: | Journal of Basic Microbiology. 57:460-470 |
| ISSN: | 0233-111X |
| DOI: | 10.1002/jobm.201700008 |
| Popis: | Drug resistance is a phenomenon where by an organism becomes fully or partially resistant to drugs or antibiotics being used against it. Antibiotic resistance poses an exacting intimidation for people with underlying medical immune conditions or weakened immune systems. Infections caused by the enzyme extended spectrum β-lactamase (ESBL) producing multi drug resistance (MDR) Enterobacteriaceae especially Escherichia coli and Klebsiella pneumoniae are resistant to a broad range of beta lactams, including third generation cephalosporins. Among all the pathogens, these two MDR E. coli and K. pneumoniae have emerged as one of the world's greatest health threats in past two decades. The nosocomial infections caused by these ESBL producing MDR E. coli and K. pneumoniae complicated the therapy and limit treatment options. |
| Databáze: | OpenAIRE |
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