Primer trasplante de intestino en Chile: Caso clínico
Autor: | Fernando Fluxá G, Gloria González G, Rodrigo Quera P, María Teresa Santander D, Mario Ferrario B, Cristina Herzog O, Mario Uribe M, David Benavente M., Jorge Godoy L, Erwin Buckel G, Jorge Morales B, Verner Codoceo R |
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Rok vydání: | 2009 |
Předmět: |
Gastrointestinal bleeding
medicine.medical_specialty business.industry medicine.medical_treatment Transplants Immunosuppression General Medicine medicine.disease Short bowel syndrome Tacrolimus Surgery Transplantation surgical procedures operative Intestine small Sirolimus Ambulatory medicine Alemtuzumab business medicine.drug |
Zdroj: | Revista médica de Chile v.137 n.2 2009 SciELO Chile CONICYT Chile instacron:CONICYT |
ISSN: | 0034-9887 |
Popis: | Small bowel transplantation is associated with a patient survival at one and five years, of 80% and 63%, respectively. We report a 36 year-old female with short bowel syndrome, subjected to the first small bowel transplantation performed in Chile. A cadaveric graft was used. Immunosuppression was achieved by means of alemtuzumab, tacrolimus, sirolimus, micofenolate mofetil and steroids. Serial endoscopies and biopsies were performed during seven months after transplantation. The most important late complications were a drug induced renal failure, infections caused by opportunistic agents and a gastrointestinal bleeding probably induced by drugs. After 29 months of follow up, the patient is ambulatory, on oral diet only, and with no evidence of graft rejection (Rev Med Chile 2009; 137: 259-63). (Key words: Immunosuppression; Intestine, small; Transplants) |
Databáze: | OpenAIRE |
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