Acid and Pepsin Dose-Response Studies to Insulin Hypoglycaemia in a Healthy Man
| Autor: | Wilson Ry, I.W. Dymock, Cowley Dj |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty medicine.medical_treatment Blood sugar Hypoglycemia Pepsin A Pepsin Internal medicine medicine Humans Insulin Inverse correlation Gastric Juice Dose-Response Relationship Drug biology business.industry Gastroenterology Pepsin output Gastric Acidity Determination medicine.disease Stimulation Chemical Insulin hypoglycaemia Endocrinology Depression Chemical Injections Intravenous biology.protein Secretory Rate business |
| Zdroj: | Digestion. 11:90-97 |
| ISSN: | 1421-9867 0012-2823 |
| Popis: | The relationship between the secretion of acid and pepsin and degree of hypoglycaemia has been studied in response to five doses of insulin (0.0125–0.2 U/kg) given by intravenous injection in a healthy man. Two tests were carried out at each dose. Both peak acid aoutput (PAOI) and peak pepsin output (PPOI) increased with the logarithm of the dose of insulin up to 0.2 U/kg. There was a significant inverse correlation between the lowest blood glucose attained and both PAOI (r = -0.81, p I (r = -0.77, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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